Croma (Croma-Pharma® GmbH) was founded in 1976 by pharmacist couple Karin and Gerhard Prinz and has grown into a leading European manufacturer of aesthetic medical products. Built on a strong scientific foundation, the company continues to invest in innovation through dedicated in-house research and development focused on advanced biopolymers and injectable aesthetic solutions.
Croma’s highly automated manufacturing processes are designed to ensure consistent quality, stability, and product safety, supporting the brand’s reputation for precision and reliability.
As a primary UK distributor of Croma products, 4T Medical supplies the European-manufactured saypha® hyaluronic acid dermal filler range and PhilArt® polynucleotide skin boosters, trusted by aesthetic professionals worldwide.

Why choose Croma HA Fillers?
Innovative crosslinking technology
Croma uses its in-house “macro” crosslinking technology to create a stable hyaluronic acid (HA) matrix for dermal filler performance and longevity. The process aligns HA chains before cross-linking them with BDDE, forming a three-dimensional structure that increases viscosity, cohesiveness, and stability.
Highly automated, tailor-made production lines minimise human intervention and ensure consistent quality, safety, and stability. All production data is recorded for analysis, and aseptic filling with a restricted area barrier system (RABS), combined with terminal sterilisation, helps reduce the risk of contamination in medical aesthetic injectable manufacturing.

Skin Boosters
Biostimulatory injectables, including polynucleotides and HA skin boosters, are treatments designed to improve skin quality from within. They help revitalise the skin, enhance texture, and restore a natural glow through collagen stimulation and dermal hydration.
Suitable for the face and other areas such as the neck, décolleté, hands, scalp, and body, these treatments support healthier, more radiant-looking skin and are widely used in aesthetic clinic skin rejuvenation treatments.
Benefits of biostimulatory injectables:
- Improves skin firmness and elasticity for a smoother, more youthful appearance
- Deeply hydrates the skin by binding water within the tissue
- Supports natural cell regeneration, encouraging fibroblast activity and collagen production
- Helps reduce signs of ageing, photoageing, and the appearance of scars
- Provides antioxidant protection to help combat free radicals and maintain skin health

Global player in the aesthetics market. Made in Austria.
Croma (Croma-Pharma® GmbH) is a global player and challenger in the dynamically growing minimally invasive aesthetics market and a leading European manufacturer of premium quality hyaluronic acid (HA) dermal fillers and aesthetic injectables.
The company offers a comprehensive and innovative aesthetics portfolio including dermal fillers, skin boosters, and biostimulatory injectables for professional aesthetic use.







