Hyaluronic acid is a simple structural polysaccharide (complex sugar) whose basic building block is glucosaminglycan, a disaccharide consisting of glucoronic acid and N-acetyl glucosamine. Hyaluronic acid fulfils important cytological functions through the interaction with cells and regulation of the intracellular signal transfer. Hyaluronic acid is found in almost every cell in the human body, with 50% concentrated in the skin.
In a person weighing 70kg, it amounts to 15g with a daily exchange rate of about 5g. In the skin, hyaluronic acid is found in the limited extracellular space in the epidermis at a concentration of 2mg/m (i.e. highly concentrated) and surrounds the keratocytes. Hyaluronic acid is responsible for the generation of moisture balance and for the modulation of membrane permeability. It is a natural moisturiser and the most important matrix component of the connective tissue.
Hyaluronic acid is regarded as the gold standard in aesthetic dermatology and has been used for a long time in wrinkle filling, in the correction of facial defects and in the follow-up treatment of scars.
