XO Nature Exosomes
XO Nature is a plant-based exosome with 36 billion particles mixed with peptides, cytokine, miRNA, polyphenol, amino acid, and hyaluronic acid.
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XO Nature is an encapsulated plant-based exosome product formulated to support skin and hair health. The product includes a 50mg vial of powder and a 5ml vial of active solution which need to be mixed together and applied with a microneedling device or derma roller.
The powder contains a range of growth factors, including freeze-dried exosomes – 36 billion particles per vial – produced using advanced 3D cell culture technology. This ensures consistent exosome size, purification, superior quality, and safety. Derived from plant stem cells (Red Root Gromwell / Lithospermum Erythrorhizon), the exosomes are rich in soluble proteins, miRNAs, and peptides, which are highly effective for skin cell regeneration.
The active solution is formulated with:
- Hyaluronic Acid: Creates a moisture barrier to keep skin hydrated.
- Amino Acids: To reduce inflammation.
- Vitamins: Promotes skin brightening and overall skin health.
- Peptides: Stimulates collagen production.
- Glutathione: Acts as an antioxidant and brightens skin.
When combined, the product is ideal for microneedling applications. It promotes skin regeneration, reduces inflammation, brightens skin, provides antioxidant properties, promotes collagen synthesis, and supports wound healing by activating keratinocytes. It can also be applied to the scalp to aid in hair restoration.
Features & benefits
- Plant-based exosome
- Produced using advanced 3D cell culture technology to ensure consistent exosome size, purification, stability, superior quality, and safety
- Initiates signaling pathways to promote cell-cell communication, tissue repair and immune system control
- Promotes wound healing, skin regeneration and enhances elasticity, reduces inflammation, protects skin from environmental aggressors and increases hydration
- Suitable for microneedling applications – Please note XO Nature vials are not suitable for nappage / injecting
- Can be used on face or scalp
- Made in South Korea
- 100% vegan and cruelty free
Suitable for
- Fine lines and wrinkles
- Sagging skin
- Age spots
- Dry skin
- Uneven skin tone and texture
- Hair restoration
Key ingredients
Red Root Gromwell (Lithospermum Erythrorhizon) is a plant species belonging to the Boraginaceae family and classified among angiosperms. In traditional Oriental herbal medicine, it is known as “Arnebia” and has been widely used to treat various skin conditions, including eczema. It is also valued as an antiseptic for burns and skin ulcers.
This plant is recognized for its effectiveness in addressing:
- Inflammation: Reducing redness and swelling.
- Antibacterial Properties: Combating harmful microorganisms.
- Antiphlogistic Effects: Alleviating fever and inflammation.
- Immunity Development: Enhancing the body’s natural defenses.
- Blood Circulation Improvement: Promoting better oxygen and nutrient delivery.
- Wound Healing: Accelerating tissue repair and regeneration.
- Skin Conditions: Treating eczema, rashes, and ulcers.
Additionally, Red Root Gromwell-derived stem cell exosomes are rich in miRNAs and proteins, offering powerful regenerative and therapeutic properties for skin health and repair.
The active solution is formulated with:
- Hyaluronic Acid: Creates a moisture barrier to keep skin hydrated.
- Amino Acids: To reduce inflammation.
- Vitamins: Promotes skin brightening and overall skin health.
- Peptides: Stimulates collagen production.
- Glutathione: Acts as an antioxidant and brightens skin
How to use
- Draw the active liquid solution (5ml) from the vial using a sterile syringe.
- Add the solution into the second vial containing 50mg of powder, then shake the vial vigorously for 30 to 60 seconds to ensure thorough mixing.
- Draw the mixed solution with a sterile syringe and apply liberally on the treatment area before treatment with a microneedling device (roller, stamp or pen). Please note XO Nature vials are not suitable for nappage (injecting).
Ingredients
XO Nature Powder (50mg)
Lithospermum Erythrorhizon Root Extract, Glycerin, 1,2-Hexanediol, Sodium Chloride, Disodium Phosphate, Methionyl r-Clostridium Botulinum Polypeptide-1 Hexapeptide-40, Potassium Chloride, Potassium Phosphate, Sodium Hyaluronate, Polysorbate 20
XO Nature Active Solution (5ml)
Aqua, Niacinamide, Sodium Hyaluronate, Tryptophan, Inositol, Thiamine HCl, Glutathione, Omithine HCL, Arginine HCL, Sodium Bicarbonate, Folic acid, Citrulline, Nicotinamide Adenine Dinucleotide, Sodium Chloride, Glycine, Lysine, Methionine, Proline, Cystine, Pyridoxine, Cyanocobalamin, Serine, Riboflavin, Biotin, Trehalose, Mannitol, sh-polypeptide-1, sh-polypeptide-11
Size
1 pack contains 50ml vial with XO NATURE Powder and 5ml vial with XO NATURE Active Solution.








