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NucleoFill Soft Plus

NucleoFill Soft Plus is a skin booster designed to target the signs of ageing around the delicate eye area by improving the skin function without the use of tear trough filler. The low molecular weight gel, derived from natural polynucleotides, targets fine lines, dark circles, under eye bags and volume loss of the periocular area.

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NucleoFill Soft Plus is a bio-stimulant gel composed of fragments of low molecular weight polynucleotide chains. The high-density, but low molecular weight structure allows for fast penetration and effective stimulation of skin bio-regeneration processes in the periocular area. The effect of the treatment is hydration and rejuvenation of the tissue, as well as the reduction of signs of fatigue and skin ageing. The effect is visible after the first treatment but for optimal results, it’s recommended to have 2 to 4 treatments at 2 week intervals.


  • Significantly reduces lower eyelid puffiness and eyebags
  • Reduces dark circles
  • Reduces the appearance of periocular fine lines and wrinkles (crow’s feet)
  • Re-densification of the dermo-epidermal tissue
  • Bio-restructuration of deep tissues
  • Pre- and post-surgical treatment (blepharoplasty, botulinum toxin, lifting, resurfacing laser)
  • Regenerates the skin in the periocular area and targets the signs of ageing
  • Naturally derived polynucleotide gel 15mg in 2ml pre-filled syringe
  • Highly purified so well tolerated
  • Low molecular weight of about 50-100 KD
  • Nin-stinging due to a pH of between 6.8 and 7.2
  • Viscosity 28-35 Pa*s
  • Two 30G x 12mm needles included in each box
  • UKCA / CE certified (CE1936)
  • Can be combined with other treatments
Targeted treatment for the periocular area and can be combined with other treatments. Suitable for all skin types.
7.5mg/ml of polynucleotides
Pack consists of: 1 x 2ml pre-filled syringe, 7.5mg/ml of polynucleotide-based gel, 2 disposable sterile needles 30G 12mm



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