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NucleoFill Medium

NuceloFill Medium is a polynucleotide-based skin booster designed to rejuvenate the skin as well as aid in the prevention of wrinkles. With long lasting effects, it stimulates cell renewal, provides a powerful antioxidant action and deeply hydrates.

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NucleoFill Medium is a bio-stimulant gel based on purified polynucleotides (PDRNs) of natural origin with high molecular weight and medium viscosity. As an anti-ageing treatment, NucleoFill is designed to improve skin elasticity and tightness and to restore skin’s natural vitality through the bio-restructuring of the dermo-epidermal layers. For optimal results, it is recommended to undertake a course of 4 treatments at 2 week intervals, with a maintenance session every 4 months..


  • Bio-restructuring of the deep dermis
  • Moisturising effect
  • Light lifting and anti-wrinkle effect
  • Skin exposed to oxidative stress (pollution, sun exposure, smoking, lifestyle)
  • Treatment of small, depressed scars
  • Before injectables, to prolong their aesthetic effects
  • Nucleofill Medium is suitable for preventive and/or curative treatment for the first signs of ageing
  • Lifting, antioxidant, and moisturising effect
  • 2% naturally derived polynucleotide gel
  • Highly purified so well tolerated
  • High molecular weight of 2.500 KD
  • Non-stinging due to a pH of between 6.8 and 7.5
  • Viscosity 28-43 Pa * s
  • Two 30G x 12mm needles included in each box
  • UKCA / CE certified (CE1936)
Targeted treatment for first signs of aging such as fine lines, wrinkles and dullness, as well as for stressed, dehydrated skin. Suitable for all skin types.
20mg/ml of polynucleotides
Pack consists of: 1 x 1.5ml pre-filled syringe, 20mg/ml of polynucleotide-based gel, 2 disposable sterile needles 30G 12mm



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